Non-hormonal therapy for hot flushes in postmenopausal women

Primary Objective:
To examine the effectiveness of non-hormonal pharmacological treatments for relieving hot flushes in postmenopausal women.
In separate comparisons, we will assess non-hormonal treatments for their effectiveness in the relief of hot flushes:

  • Non-hormonal treatments versus placebo
  • Non-hormonal treatments versus hormonal replacement therapy
  • Non-hormonal treatments versus no-treatment control group


Secondary Objectives:
To determine the adverse effects of non-hormonal treatments.
To evaluate the impact on quality of life of non-hormonal treatments versus no-treatment control, placebo or hormonal replacement therapy.

This is a protocol.

Health topics: