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6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease

This is a protocol for a Cochrane Review (intervention). The objectives are as follows:

To determine the efficacy and safety of a 6-thioguanine nucleotide (6-TGN) metabolite-based dosing strategy for maintenance of remission using azathioprine or mercaptopurine in Crohn's disease and ulcerative colitis.

This is a protocol.

Health topics:

Gastroenterology & hepatology > Inflammatory bowel disease > Crohn's disease: maintenance of remission

Gastroenterology & hepatology > Inflammatory bowel disease > Ulcerative colitis: maintenance of remission

Published:

24 January 2023

Authors:

Mateen BA, Patel M, Akobeng AK, Gordon M, Hayee B

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the Cochrane Library

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Citation
Mateen BA, Patel M, Akobeng AK, Gordon M, Hayee B. 6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease (Protocol). Cochrane Database of Systematic Reviews 2021, Issue 10. Art. No.: CD014795. DOI: 10.1002/14651858.CD014795.