Cochrane Heart, Stroke and Circulation


About us

Stroke, heart disease, hypertension, and peripheral vascular disease are collectively the leading global causes of mortality, morbidity, and disease burden using disability-adjusted life years. As the global population ages, these conditions will become more common. Cardiovascular disease is one of the 12 broad topic areas of importance identified by Cochrane because they are relevant to the United Nations Sustainable Development Goals and the World Health Organisation (WHO). With the pattern of disease changing, a single disease focus in reviews is becoming less applicable to the general population, therefore Cochrane has brought together the four existing Cochrane groups – Cochrane Heart, Cochrane Hypertension, Cochrane Stroke, and Cochrane Vascular – into a single Thematic Group.

Cochrane Heart, Stroke and Circulation shares collective expertise and knowledge and ensures that evidence synthesis in cardiovascular disease reflects the multimorbidity paradigm, the large global burden of vascular disease (increasing especially in developing countries), and the continuous development of interventions and diagnostic tests for these conditions.


Team

Gillian Mead

Gillian Mead: Group Leader - University of Edinburgh.

Alex Todhunter-Brown Alex Todhunter-Brown: Group Leader - Glasgow Caledonian University.
Rui Providencia Rui Providencia: Group Leader - University College London.
Rod Taylor Rod Taylor: Group Leader - University of Glasgow.
Jackie Price Jackie Price: Group Leader - University of Edinburgh.
Gerry Stansby Gerry Stansby: Group Leader - Newcastle University.
Jim Wright Jim Wright: Group Leader - University of British Columbia.
Juan Erviti Juan Erviti: Group Leader - Cochrane Iberoamerica, Navarre Associate Centre.

Our Plans

Long term sustainability of these activities outlined below are subject to appropriate funding, which is actively being sought.

Broadly, our work plan is designed to enable us to establish an inclusive management structure, and define activities and outputs in more detail. We will also develop and submit funding applications and explore alternative models of funding (e.g., by approaching our institutions).

Further specific objectives within the first 18 months are to:

  1. Map existing reviews and identify areas of overlap in terms of interventions, and diseases. This has been done for Cochrane Stroke and could be repeated for the other disease groups.
  2. Synthesise existing priorities relating to Vascular Diseases set by James Lind Alliance and other patient/carers surveys. The Stroke Association (UK) performed a major priority-setting exercise in June 2021. The main findings have been published (top 10 areas in Life after stroke and acute care/secondary prevention) but there are other important priorities below that which we can scrutinise too, and explore how these map to Cochrane reviews.
  3. Identify a programme of high priority reviews and updates (this could include de novo reviews, update reviews, overviews), determine whether they require complex methodological input, and form plans for the conduct of these (e.g. funding applications for specific reviews; updates conducted by post-graduate students or early career researchers, with support from experienced reviewers - see also Cochrane's Early Career Professionals Network).
  4. Establish our Thematic Group management structure, ensuring we have adequate representation of disease /topic experts and geographical diversity of members, including from low and middle-income countries
  5. Provide content expertise to identify priorities in these disease areas, as required by Cochrane central team
  6. Provide topic, content and editorial expertise to the Cochrane central team, to support the centralised editorial service, as required
  7. Co-create a consumer engagement strategy, and ensure meaningful engagement of patients, carers and stakeholders
  8. Co-create a dissemination strategy, with a focus on the facilitation of knowledge translation, and develop mechanisms to disseminate updated and new reviews published by Cochrane.
  9. Maintain up-to-date trials register, as this is utilised by a number of Guideline developers (subject to resources available to engage an information specialist).
  10. Explore options to automate study identification.

Published Reviews

Heart disease
Hypertension
Stroke
Vascular disease


News

  • People at the meetingThe Cochrane Heart Stroke and Circulation thematic group hosted a satellite meeting at the Global Evidence Summit in Prague, on Monday 9th September 2024. We were extremely grateful to the Academy of Medical Sciences for awarding us a networking grant which enabled us to host the meeting.  We were delighted that several group members were able to attend in person and we also had global representation from members on-line. We made important steps forward in deciding how to prioritise reviews for updates, how to identify new topics for new reviews, how to support authors, how to work more closely with Cochrane Central, and how a Board will be structured to manage our group going forwards. More news on that to follow!
    The Summit allowed us to meet with other Cochrane members informally and to identify other clinicians and researchers to join our group.
    Here you can read about some Highlights and Key Learning from the Summit
  • We are delighted to say that we have been successful in obtaining a networking grant from the Academy of Medical Sciences, from April 2024 to March 2025 to support our meetings (including a face-to-face meeting in Prague) and the development of other grants. Grant holders of the Academy of Medical Sciences Grant include:  Gillian Mead and Leon Flicker (co-leads), and Simiao Wu (China), Stefan Engelter (Switzerland), Sanghamitra Pati (India), David Williams (Ireland) and Valery Feigin (New Zealand).
  • A PhD Fellowship at University of Edinburgh will focus on the development of new methods to address and report multimorbidity in Cochrane reviews. Applications open until 28 August 2024. More details and application link.
  • The last few months have been busy for us. We have written grant applications to support our work and will let you know the outcomes of these as soon as we can.
  • We continue to support Cochrane Central by reviewing and contributing to proposals about new reviews.
    Several of us are also members of NESSIE (NIHR EVIDENCE SYNTHESIS SCOTLAND INITIATIVE).
    We continue to expand our group with new members. We welcome new members with an interest in evidence synthesis in vascular disease to join us.
    In 2024 we will continue with our efforts to secure substantive funding.
    (December2023)

  • Introducing Cochrane Heart, Stroke and Circulation
    (May 2023)

Contact us

Email: cochraneheartstrokecirculation@ed.ac.uk


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